Avastin Approved in First-Line Lung Cancer Treatment

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Genentech received approval from the FDA for Avastin to be used in combination with carboplatin and paclitaxel chemotherapy for the first-line treatment of patients with unresectable, locally advanced, recurrent or metastatic non-squamous, non-small cell lung cancer (NSCLC), the most common type of lung cancer. The approval is based on a Phase III study (E4599) that showed Avastin in combination with chemotherapy resulted in a 25% improvement in overall survival compared to chemotherapy alone. ...

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